Literature summary extracted from

Krishnan, B.; Massilamany, C.; Basavalingappa, R.H.; Gangaplara, A.; Kang, G.; Li, Q.; Uzal, F.A.; Strande, J.L.; Delhon, G.A.; Riethoven, J.J.; Steffen, D.; Reddy, J.
Branched chain alpha-ketoacid dehydrogenase kinase 111-130, a T cell epitope that induces both autoimmune myocarditis and hepatitis in A/J mice (2017), Immun. Inflamm. Dis., 5, 421-434 .

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining
2.7.11.4	mitochondrion	-	Mus musculus	5739	-

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.11.4	Mus musculus	O55028	-	-

Synonyms

EC Number	Synonyms	Comment	Organism
2.7.11.4	BCKDK	-	Mus musculus
2.7.11.4	branched chain alpha-ketoacid dehydrogenase kinase	-	Mus musculus

General Information

EC Number	General Information	Comment	Organism
2.7.11.4	physiological function	BCKDk contains multiple epitopes that can induce myocarditis. The BCKDk 111-130 is the primary epitope that induces both autoimmune myocarditis and hepatitis in A/J mice. The disease induced by BCKDk peptides can serve as a useful model to study the autoimmune events of inflammatory heart and liver diseases	Mus musculus

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Release 2023.1 (January 2023)